Chapter 4 of 62
Fluid Science & Indications
Fluid & Electrolyte Physiology
Understanding body fluid distribution is fundamental to safe IV therapy. The body's water is distributed across compartments, and IV solutions interact with these compartments differently.
Body Fluid Distribution:
Key Points
- Intracellular Fluid (ICF) constitutes approximately 2/3 of total body water
- Extracellular Fluid (ECF) constitutes approximately 1/3 (intravascular + interstitial)
- Isotonic solutions primarily expand intravascular space
- Excess administration may result in peripheral edema
- Excess administration may result in elevated blood pressure
- Excess administration may result in pulmonary congestion
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