Chapter 12 of 62
Infection Control & Preparation
Additive Compatibility & Stability Principles
Before mixing any additives with IV solutions, compatibility and stability must be verified. Incompatible combinations can result in precipitation, reduced efficacy, or patient harm.
Before mixing, always:
Key Points
- Verify compatibility with saline or LR
- Confirm proper dilution ratios
- Check manufacturer stability guidance
- Avoid precipitation or cloudiness
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